Treating children and adults with Gilles de la Tourette syndrome (GTS) remains a clinical challenge and typically requires a multidisciplinary approach, owing to the complexity of the disorder and the frequent presence of comorbidities such as obsessive-compulsive disorder and attention-deficit/hyperactivity disorder. This chapter focuses on the pharmacologic management of tics in the context of GTS. It reviews key considerations in the selection of therapeutic agents from the broad range of…
