Genetic susceptibility for neurodevelopmental disorders in children born to women with epilepsy

Children of women with epilepsy have higher rates of neurodevelopmental disorders including attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD), than the general population. This likely reflects a complex gene-environment interplay, but the specific contribution of genetic susceptibility, independent of in utero antiseizure medication exposure, remains unclear. The objective of this study was to evaluate whether polygenic risk scores (PRSs) for ADHD and ASD are…

via https://pubmed.ncbi.nlm.nih.gov/41907316/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1lqZ3NPYysePVKsoyz66mDSgu4veDGJwnUBS47TBQPoOuNZY5J&fc=None&ff=20260408011005&v=2.19.0.post6+133c1fe


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