White matter properties in fronto-parietal tracts predict maladaptive functional activation and deficient response inhibition in ADHD

Response inhibition is a key characteristic of adaptive human behaviour. However, in attention deficit hyperactivity disorder (ADHD) it is often impaired. Previous neuroimaging investigations implicate a myriad of brain networks in response inhibition, making it more difficult to understand and overcome response inhibition difficulties. Recently, it has been suggested that a specific fronto-parietal functional circuitry between the inferior frontal gyrus (IFG) and the intraparietal sulcus (IPS),…

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