In preclinical research, animal models are a valid alternative for studying both the genetics and environmental factors related to human psychopathologies. Indeed, in the last few decades, a great emphasis has been placed on the spontaneously hypertensive rat (SHR) inbred strain as an attention-deficit/hyperactivity disorder (ADHD) animal model. Therefore, this systematic review and meta-analysis aim to evaluate the effects of environmental enrichment (EE) on the behavior profile of the SHRs….
