Standardized methodology for assessing the presence, variants and area of the interthalamic adhesion using anatomical MRI (SNAP-IA): multicentric validation on 565 healthy individuals and multiple neurological disorders

The interthalamic adhesion (IA) connects both thalami. Emerging research suggests it may support thalamo-cortical connectivity and could be involved in neurodevelopmental and neuropsychiatric conditions. However, inconsistent MRI evaluation hinders progress on this subject. We developed SNAP-IA, a standardized anatomical imaging protocol for consistent IA identification and quantification. This work leveraged the expertise from seven research teams (Toulouse, Santiago, Southampton, Lausanne,…

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