Prenatal IgE as a Risk Factor for the Development of Childhood Neurodevelopmental Disorders

Background: Few studies have examined if maternal allergic disease is associated with an offspring’s neurodevelopment. We hypothesized that Th-2 biased maternal immune function assessed as total serum immunoglobulin (Ig) E is associated with attention deficit hyperactivity disorder (ADHD). Methods: Data are from the Wayne County Health, Environment, Allergy, and Asthma Longitudinal Study (WHEALS), a racially and socioeconomically diverse birth cohort in metropolitan Detroit, Michigan. Maternal…


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