CONCLUSIONS: In this exploratory analysis, SNRIs rather than SSRIs were associated with self-reported clenching, in contrast to the predominance of SSRIs in case-report literature. Greater CNS polypharmacy was associated with higher odds of self-reported clenching, and SSRI-SNRI coexposure emerged as a hypothesis-generating signal requiring confirmatory analysis.Knowledge Transfer Statement:Evidence linking specific central nervous system (CNS) medications to bruxism has relied predominantly on…
