Pediatric Bone Marrow Transplantation: Psychopathologic Features in Recipients along with Siblings.

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Pediatric Bone Marrow Transplantation: Psychopathologic Features in Recipients along with Siblings.

Psychooncology. 2019 Jul 19;:

Authors: Erden S, Kuşkonmaz BB, Çetinkaya DU, Ünal F, Özsungur B

Abstract
OBJECTIVE: To analyze the development of psychopathology in recipients along with their donor and non-donor siblings and the relationship with the bone marrow transplantation (BMT) process.
METHODS: All children were interviewed using the Kiddie Schedule for Affective Disorders and Schizophrenia to assess psychopathology. The depression and anxiety symptoms and self-esteem of children and adolescents were evaluated using the Children’s Depression Inventory, State-Trait Anxiety Inventory for Children, State-Trait Anxiety Inventory, Rosenberg Self-Esteem Scale.
RESULTS: In this study, the depressive symptom level was found significantly higher in the donor group compared with the non-donor group. State anxiety symptoms were higher in the BMT group (p<0.05). There were no significant differences in trait anxiety symptoms. Self-respect was higher in children in the donor group compared than in those in the BMT group (p<0.05). During the transplant process, children with bone marrow transplants had a higher prevalence of depression, anxiety disorder, and attention-deficit/hyperactivity disorder, and non-donor siblings had a higher prevalence of depressive disorder, anxiety disorder, and attention-deficit/hyperactivity disorder compared with society in general.
CONCLUSION: Physicians should deal with the family as a whole, not just their patient, and should be aware of the psychiatric risk of other siblings during the assessment.

PMID: 31322797 [PubMed – as supplied by publisher]

via https://www.ncbi.nlm.nih.gov/pubmed/31322797?dopt=Abstract