Pediatric Bone Health and Attention-Deficit/Hyperactivity Disorder (ADHD) Stimulants: Raising Awareness of Avascular Necrosis Risk

Avascular necrosis (AVN) is a rare but serious complication of pediatric musculoskeletal injury, traditionally associated with corticosteroid use, trauma, or systemic disease. However, stimulant medications used to treat attention-deficit/hyperactivity disorder (ADHD) may contribute to AVN risk through effects on bone metabolism and vascular tone, including reduced bone mineral density and increased sympathetic activity. In clinical practice, we observed a case of AVN in a child with ADHD…

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