Neurodevelopmental and psychiatric disorders, such as attention deficit hyperactivity disorder or autism spectrum disorder, have been intricately linked to structural impairments and compromised permeability of the blood-brain barrier (BBB). Occludin (ocln) is a tight junction (TJ) protein known for its role in maintaining BBB integrity. In the present manuscript, we report unexpected connection between ocln deficiency and behavioral alterations resembling neurodevelopmental and psychiatric…
