Noradrenaline reuptake inhibitors (NRIs) for attention deficit hyperactivity disorder (ADHD) in adults

RationaleAttention deficit hyperactivity disorder (ADHD) in adults is controversial. Noradrenaline reuptake inhibitors (NRIs) are used for treatment. It’s unclear how helpful/harmful they are.ObjectivesThis review brings together available evidence to evaluate the benefits and harms of NRIs in adults with ADHD.MethodsWe searched for all randomised controlled trials that compared NRIs to placebo/no treatment in bibliographic databases (April 2025) and synthesised their results. We assessed the…

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