Long-Term Benefits of Chronic 5-HT2A Antagonist and 5-HT1A Agonist Treatment on ADHD Behavior in Juvenile Spontaneously Hypertensive Rats

CONCLUSION: These findings suggest that dysregulation of 5-HT1A and DA-D2 receptors may contribute to ADHD, and monotherapy with either a 5-HT1A receptor stimulator or a 5-HT2A receptor inhibitor can effectively alleviate core ADHD symptoms long-term, likely through indirect DA system modulation.

via https://pubmed.ncbi.nlm.nih.gov/41742614/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1lqZ3NPYysePVKsoyz66mDSgu4veDGJwnUBS47TBQPoOuNZY5J&fc=None&ff=20260308011005&v=2.19.0.post6+133c1fe