Frequent use of methylphenidate causes reduction in sperm production and sperm quality in adult balb/c mice

Methylphenidate is a psychostimulant used mainly in the treatment of attention deficit hyperactivity disorder (ADHD). The present study evaluated the effects of the drug on the testicles of adult mice, through morphological, histometric, hormonal, and sperm evaluations. Twenty-four Balb /c mice were randomly divided into three experimental groups (n = 8). Group 01: control (distilled water); Group 02: 20 mg/kg/day of methylphenidate; Group 03: 40 mg/kg/day of methylphenidate. The treatment…

via https://pubmed.ncbi.nlm.nih.gov/40532595/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1HYeX0emtvYgH07Wkz0a8n9otrdMd-JIklc_uo0I5vh1u9WMEy&fc=None&ff=20250620010806&v=2.18.0.post9+e462414