Distinct Effects of Psychiatric Disorder Diagnoses and Severe Emotional Dysregulation on Matrix Metalloproteinase-9, Proinflammatory Cytokines, and Inhibitory Control Function in Adolescents with Attention Deficit Hyperactivity Disorder or First-Episode Major Affective Disorders

BACKGROUND: Severe emotional dysregulation (SED) may represent an endophenotype of attention deficit hyperactivity disorder (ADHD) and major affective disorders. However, the specific effects of SED and related psychiatric disorders, including ADHD, bipolar disorder (BD), and major depressive disorder (MDD), on matrix metalloproteinase-9 (MMP-9) and proinflammatory cytokine levels and on inhibitory control function remain unclear.

via https://pubmed.ncbi.nlm.nih.gov/40219625/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1lqZ3NPYysePVKsoyz66mDSgu4veDGJwnUBS47TBQPoOuNZY5J&fc=None&ff=20250423011007&v=2.18.0.post9+e462414