Methylphenidate (MPH) is a widely used pharmacological treatment for attention deficit/hyperactivity disorder (ADHD), which increases the extracellular dopamine and noradrenaline level by inhibiting their reuptake. Despite reported improvements in cognitive functions, the influence of medication history on MPH efficacy and its impact on attentional brain regions remain unclear. We examined 36 adults with ADHD using a within-subject design. Participants completed a central cue version of the…
