Child behavior checklist dysregulation profile in children with disruptive behavior disorders: A longitudinal study.

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Child behavior checklist dysregulation profile in children with disruptive behavior disorders: A longitudinal study.

J Affect Disord. 2015 Nov 1;186:249-53

Authors: Masi G, Pisano S, Milone A, Muratori P

Abstract
BACKGROUND: A Child Behavior Checklist (CBCL) profile defined as Dysregulation Profile (DP) (scores 2 standard deviations or more in anxiety/depression, aggression, attention subscales) has been correlated to poor emotional and behavioral self-regulation. The clinical meaning and the prognostic implications of CBCL-DP are still debated, although it seems associated with severe psychopathology and poor adjustment.
METHOD: In the present study, we used the CBCL-DP score to examine the adolescent outcomes (psychiatric diagnosis, substance use, psychiatric hospitalization) in 80 referred children with disruptive behavior disorders -DBD- (Oppositional Defiant Disorder or conduct disorder), aged 8-9 years, 72 males (90%) and 8 females (10%), followed-up until the age of 14-15 years.
RESULTS: Children with higher score on the CBCL-DP profile were at increased risk for presenting ADHD and mood disorders in adolescence. While ADHD in adolescence was predicted also by an ADHD diagnosis during childhood, CBCL-DP score was the only significant predictor of a mood disorder at 14-15 years. On the contrary, CBCL-DP score was not associated with a higher risk of conduct disorder, substance use and hospitalizations in adolescence. A cost-effective and reliable diagnostic measure such as the CBCL may be a part of the diagnostic procedure aimed to capture these at-risk children, to monitor their natural history up to adolescence, and to prevent the risk of a full-blown mood disorder.
LIMITATIONS: The small sample size and a selection bias of severe patients with DBD limit the generalization of the findings.

PMID: 26254616 [PubMed – indexed for MEDLINE]

via http://www.ncbi.nlm.nih.gov/pubmed/26254616?dopt=Abstract