Causal association between lipid profile and mental disorders: evidence from a bidirectional Mendelian randomization study

CONCLUSIONS: These findings suggest that genetically predicted TG levels may influence anxiety risk, while genetic predisposition to MDD and ADHD may contribute to dyslipidemia. Our study provides genetic evidence supporting a potential causal interplay between lipid metabolism and mental disorders, highlighting the need for interdisciplinary care and personalized monitoring to address psycho-metabolic comorbidities.

via https://pubmed.ncbi.nlm.nih.gov/41489637/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1lqZ3NPYysePVKsoyz66mDSgu4veDGJwnUBS47TBQPoOuNZY5J&fc=None&ff=20260116011007&v=2.18.0.post22+67771e2