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Body focused repetitive behavior disorders: Significance of family history.
Compr Psychiatry. 2016 Apr;66:187-92
Authors: Redden SA, Leppink EW, Grant JE
Abstract
BACKGROUND: The significance of family history in body-focused repetitive behavior disorders (BFRBs) (i.e. trichotillomania and skin picking) has received scant research attention. We sought to understand the clinical and cognitive impact of having a first-degree relative with a BFRB or a substance use disorder (SUD).
METHODS: 265 participants with BFRBs undertook clinical and neurocognitive evaluations. Those with a first-degree relative with a BFRB or an SUD were compared to those without on a number of clinical and cognitive measures.
RESULTS: 77 (29.1%) participants had a first-degree family member with a BFRB and 59 (22.2%) had a first-degree family member with an SUD. In terms of clinical severity, the amount of time spent picking or pulling per day in the past week was higher among those with a first-degree relative with an SUD. There were a higher rate of ADHD and higher HAM-D scores among those with a positive family history of an SUD. There were no significant cognitive differences based on family history.
CONCLUSIONS: These results indicate that among those with BFRBs, having a first-degree family member with an SUD may be associated with a unique clinical and cognitive presentation. Whether family history also is associated with differential response to treatments awaits further research.
PMID: 26995252 [PubMed – indexed for MEDLINE]
via https://www.ncbi.nlm.nih.gov/pubmed/26995252?dopt=Abstract