The endocannabinoid system (ECS) is a lipid-derived signaling network composed of cannabinoid receptors, endogenous ligands, and metabolic enzymes. Through its widespread neuromodulatory functions, the ECS regulates dopaminergic, noradrenergic, and glutamatergic pathways that are critical for attention and behavioral control. Emerging evidence indicates that dysregulation of ECS components may contribute to the pathophysiology of attention deficit hyperactivity disorder (ADHD). This review…
