Attention-deficit/hyperactivity disorder stimulant use is associated with reduced semen volume in reproductive-age men: a multi-center analysis

Stimulant medications are increasingly prescribed for attention-deficit/hyperactivity disorder (ADHD) in men of reproductive age, yet their impact on semen quality remains poorly characterized. We aimed to evaluate whether recent stimulant exposure would negatively affect semen parameters in reproductive-age men with ADHD. We performed a multi-center retrospective analysis of 2039 men aged 18-40 years with a diagnosis of ADHD and available semen volume data between 1995-2025. We excluded men…

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