Lack of beneficial effect of planned treatment interruption in adults with ADHD treated with methylphenidate – clinical evidence

CONCLUSIONS: In adult men receiving stable MPH treatment, planned weekend breaks were not associated with a clear overall advantage and were linked to less favorable diary-based behavioral functioning and more frequent selected self-reported cardiovascular adverse effects. Routine weekend discontinuation should not be assumed to improve treatment quality.

via https://pubmed.ncbi.nlm.nih.gov/42679659/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1HYeX0emtvYgH07Wkz0a8n9otrdMd-JIklc_uo0I5vh1u9WMEy&fc=None&ff=20260902010805&v=2.20.1