Inattention and hyperfocus mediate the association between prefrontal cortical thickness and problematic usage of the internet, with frequent gaming-related problems, independent of a formal ADHD diagnosis

CONCLUSION: In individuals with PUI, inattention and hyperfocus may mediate the relationship between PFC thickness and PUI severity, irrespective of a formal ADHD diagnosis. Further, distinct neurobiological subtypes of PUI may support the development of personalized, symptom-targeted interventions.

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