Concomitant activation of D₁ dopamine and α_2A adrenergic receptors improves cognition better than methylphenidate in two rodent behavioral tests

CONCLUSIONS: These findings suggest that potential benefits may emerge from the coadministration of selective agents (e.g., α(2A) and D(1) agonists) and should be considered for further study, especially regarding individuals with decrements in cognitive function.

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