Methylphenidate (MPH) is a psychostimulant widely prescribed for the treatment of attention-deficit/hyperactivity disorder (ADHD) and narcolepsy. Its primary mechanism of action involves inhibition of dopamine and noradrenaline reuptake. The non-medical use of methylphenidate by individuals without neurodevelopmental disorders has been increasing and becoming widespread in contexts of misuse and as a nootropic. This translational study aims to investigate the long-term effects of repeated MPH…
