Metabolomic alterations in cord blood improve the prediction of childhood-onset neurodevelopmental disorders

We aimed to identify cord blood metabolic measures associated with childhood-onset neurodevelopmental disorders (NDDs) and to examine whether they improve prediction beyond known early-life risk factors. In a prospective study of 858 children followed to a median age of 14.1 years (IQR 13.7-14.8), cord blood levels of 110 metabolic measures were assessed at birth and NDD diagnoses obtained from nationwide register. We identified 12 cord blood metabolic measures together explaining 5.0% of…

via https://pubmed.ncbi.nlm.nih.gov/42350403/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1lqZ3NPYysePVKsoyz66mDSgu4veDGJwnUBS47TBQPoOuNZY5J&fc=None&ff=20260704011008&v=2.20.0


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