Maternal immune activation in mice recapitulates features of attention-deficit/hyperactivity disorder (ADHD) in susceptible offspring

Prenatal exposure to infectious or non-infectious maternal immune activation (MIA) represents a transdiagnostic environmental risk factor for psychiatric and neurodevelopmental disorders. Building on previous findings of locomotor hyperactivity in a subset of male MIA offspring, the present study investigated whether viral-like MIA in mice recapitulates features of attention-deficit/hyperactivity disorder (ADHD) in this subgroup. We show that 40-50% of MIA-exposed male offspring develop…

via https://pubmed.ncbi.nlm.nih.gov/41764291/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1L37KAMf2b_g4WEK3LmdFuKZu9pO3cN7u4ZmO9PPCPeBLMIw1q&fc=None&ff=20260309020906&v=2.19.0.post6+133c1fe


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