Atomoxetine (ATX), a selective noradrenaline reuptake inhibitor that is widely used to treat attention-deficit hyperactivity disorder, has recently been suggested to exert neuroprotective effects by modulating inflammatory responses in the central nervous system, particularly in microglial cells. In this study, we investigated the effect of ATX on BV-2 microglial cells. Upon administration of 50 µM ATX, a significant suppression of lipopolysaccharide (LPS)-induced nitric oxide (NO) production…
