Association between isolated single umbilical artery and neurodevelopmental disorders: population-based study

CONCLUSION: iSUA was weakly associated with ID and ADHD, but not with other NDD. These associations were influenced by sex and were mediated by < 10% by preterm birth or SGA. The absence of associations of iSUA with other NDD is reassuring, and this finding is useful in the counseling of expectant parents of fetuses with iSUA. © 2026 International Society of Ultrasound in Obstetrics and Gynecology.

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