CLINICAL CHARACTERISTICS: Cantú syndrome is characterized by congenital hypertrichosis; distinctive coarse facial features (including broad nasal bridge, wide mouth with thick vermilion of the upper and lower lips, and macroglossia); enlarged heart with enhanced systolic function, as well as pericardial effusion and, in many, a large patent ductus arteriosus (PDA) requiring repair; and musculoskeletal abnormalities (thickening of the calvaria, broad ribs, scoliosis, flaring of the metaphyses,…
