Executive function mediates the effects of genetic liability to schizophrenia on behavior and functioning in a community sample of children and adolescents

CONCLUSIONS: PRS-SZ was associated with poorer EF, which in turn mediated its associations with increased general psychopathology (p-factor) and anxiety symptoms, and reduced school performance in this community youth sample. EF may represent a hub through which PRS-SZ contributes to negative behavioral and functional outcomes.

via https://pubmed.ncbi.nlm.nih.gov/41592516/?utm_source=Other&utm_medium=rss&utm_campaign=None&utm_content=1L37KAMf2b_g4WEK3LmdFuKZu9pO3cN7u4ZmO9PPCPeBLMIw1q&fc=None&ff=20260205010906&v=2.18.0.post22+67771e2