Citicoline and phosphatidylserine are considered safe compounds with potential cognitive and behavioral benefits in the management of attentiondeficit/hyperactivity disorder (ADHD). However, their safety profiles have not been sufficiently characterized. A case is presented of a 7-year-old boy with ADHD who developed marked irritability, agitation, and a suicide attempt shortly after starting a combination of methylphenidate, phosphatidylserine (100 mg/day), and citicoline (250 mg/day). During…
