Despite recent abundant studies on animal models of attention-deficit/hyperactivity disorder (ADHD), a complete model remains unestablished. In this study, we investigated the potential of STAM1-deficient mice as a new animal model for ADHD. STAM1-deficient mice escaped from a high platform significantly faster than wild-type mice, indicating ADHD-like impulsivity. Low anxiety-like behavior in STAM1-deficient mice was also confirmed in an elevated plus maze and light and dark compartment test….
