Objective: The current study aimed to investigate the efficacy of probiotics in alleviating anxiety in children and adolescents. Methods: Randomized placebo-controlled trials (RCTs) recruiting children and adolescents were identified through searching major databases using the main keywords “Probiotics” and “Anxiety.” Outcomes included improvement in anxiety and treatment acceptability. Continuous and categorical data were expressed as effect size based on standardized mean difference (SMD) and…
