Attention deficit hyperactivity disorder (ADHD) is a childhood-onset neurodevelopmental disorder with a large genetic component¹. It affects around 5% of children and 2.5% of adults², and is associated with several severe outcomes^(3-11). Common genetic variants associated with the disorder have been identified^(12,13), but the role of rare variants in ADHD is mostly unknown. Here, by analysing rare coding variants in exome-sequencing data from 8,895 individuals with ADHD and 53,780 control…
