Background and Aim: Colorectal carcinogenesis involves two distinct pathways, the serrated neoplasia pathway and adenoma (AD)-carcinoma sequence, whose precursors are sessile serrated lesion (SSL) and traditional AD, respectively. MicroRNAs (miRNAs) regulate gene expression and play a crucial role in colorectal tumorigenesis. This study investigated miRNA expression in the precursors and early invasive carcinomas of the two pathways. Methods: Using real-time reverse transcription polymerase…
