Rodent models of attention-deficit hyperactivity disorder: An updated framework for model validation and therapeutic drug discovery

There are over twenty rodent models of Attention-Deficit Hyperactivity Disorder (ADHD), with most reflecting a recognized ADHD subtype. Of these, only five rat models (Neonatal 6-Hydroxydopamine, Spontaneously Hypertensive Rat, Prenatal Alcohol Exposure, Prenatal Nicotine Exposure, and Lphn3 Knockout) and three mouse models (Dopamine Transporter Knockout, Neurokinin-1 Receptor Knockout, and Prenatal Nicotine Exposure) have a sufficient number of publications to explore their suitability for…

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