REiNS: Recommendations for Social Skills Endpoints for Clinical Trials in Neurofibromatosis Type 1

CONCLUSIONS: Each of the two measures assesses different aspects of social functioning. The SSIS-RS is appropriate for studies focused on broader social functioning, while the SRS-2 is best for studies targeting problematic social behaviors associated with ASD. Researchers will need to consider the goals of their study when choosing a measure, and specific recommendations for their use are provided.


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