ADHD is increasingly recognised as a cause of functional impairment in adults. Treatment guidelines recommend stimulants as the first-line treatment for adult ADHD, but concerns exist about long-term efficacy and potential tolerance. We investigated the long-term effect of stimulant therapy on brain morphometry in individuals with ADHD. We obtained structural MRI data from the UCLA Consortium for Neuropsychiatric Phenomics for 26 adults with ADHD. We compared grey matter volume, cortical…
