Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) are both highly prevalent disorders and frequently co-occur. The underlying neurological mechanisms of the co-occurrence of ASD and ADHD (ASD + ADHD) remain unknown. This study focuses on investigating the effective connectivity (EC) alterations within the triple network model in individuals with ASD + ADHD. Resting-state functional magnetic resonance imaging data were obtained from 44 individuals with ASD + ADHD,…